Validation of the REM sleep behavior disorder screening questionnaire in the Czech population

Background: Idiopathic rapid eye movement sleep behavior disorder (iRBD) affects 1-2% of people over 60 years of age and presents a high risk of developing a neurodegenerative disorder from the group of synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Therefore, screening tools are needed. In 2007, the rapid eye movement sleep behavior disorder screening questionnaire (RBD-SQ) was developed and has been translated into several languages. The aim of study was to assess the validity and reliability of the Czech version of the RBD-SQ in a mixed population of sleep clinic patients, supplemented by healthy volunteers and RBD patients.

Methods: Participants included 81 iRBD patients, 205 patients with other sleep disorders (obstructive sleep apnea, insomnia, restless legs syndrome and periodic limb movement disorder, other parasomnias, or central hypersomnias including narcolepsy) and 20 healthy volunteers.

Conclusions: The Czech version of the RBD-SQ is a sensitive tool for screening for iRBD patients and helps to identify subjects for complete clinical workup.

Keywords: Rapid eye movement sleep behavior disorder; Screening for synucleinopathy; Self administered questionnaire.

Conflict of interest statement

The authors declare that they have no competing interests.

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References

    1. American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed. Darien, IL; 2014.
    1. Kang SH, Yoon IY, Lee SD, Han JW, Kim TH, Kim KW. REM sleep behavior disorder in the Korean elderly population: prevalence and clinical characteristics. Sleep. 2013;36(8):1147–1152. doi: 10.5665/sleep.2874. - DOI - PMC - PubMed
    1. Pujol M, Pujol J, Alonso T, Fuentes A, Pallerola M, Freixenet J, Barbe F, Salamero M, Santamaria J, Iranzo A. Idiopathic REM sleep behavior disorder in the elderly Spanish community: a primary care center study with a two-stage design using video-polysomnography. Sleep Med. 2017;40:116–121. doi: 10.1016/j.sleep.2017.07.021. - DOI - PubMed
    1. Iranzo A, Fernandez-Arcos A, Tolosa E, Serradell M, Molinuevo JL, Valldeoriola F, Gelpi E, Vilaseca I, Sanchez-Valle R, Llado A, et al. Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients. PLoS One. 2014;9(2):e89741. doi: 10.1371/journal.pone.0089741. - DOI - PMC - PubMed
    1. Iranzo A, Molinuevo JL, Santamaria J, Serradell M, Marti MJ, Valldeoriola F, Tolosa E. Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. The Lancet Neurology. 2006;5(7):572–577. doi: 10.1016/S1474-4422(06)70476-8. - DOI - PubMed